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Terbinafine Hydrochloride powder Terbinafine Hcl tablets Terbinafine

  • Product Name Terbinafine
  • Appearance White crystalline powder
  • CAS No. 91161-71-6
  • Chemical Formula C21H25N
  • Molecular weight 291.438
  • Melting point 203-205 °C
  • Boiling point 417.9±33.0 °C(Predicted)
  • Density 1.007±0.06 g/cm3(Predicted)

Detailed Description

Terbinafine powder typically appears White crystalline powder. The powder has a smooth and uniform texture,and it is generally odorless.The main function of terbinafine powder is as an antifungal agent.It works by inhibiting the enzyme squalene epoxidase,which is essential for the biosynthesis of ergosterol,a critical component of the fungal cell membrane.By disrupting the production of ergosterol,terbinafine weakens the fungal cell membrane,leading to fungal cell death.This mechanism of action distinguishes terbinafine from other antifungal medications and contributes to its effectiveness against a broad spectrum of fungi,including dermatophytes,molds,and certain yeasts.Terbinafine powder is soluble in organic solvents and exhibits stability under appropriate storage conditions.

Terbinafine powder has various applications within the pharmaceutical and healthcare sectors:
1.Pharmaceutical Formulations:Terbinafine powder serves as an active pharmaceutical ingredient(API)in the production of various dosage forms,including creams,gels,ointments,and topical solutions.When incorporated into these formulations,terbinafine provides a localized and targeted approach to treating fungal infections of the skin,such as athlete's foot(tinea pedis),jock itch(tinea cruris),and ringworm(tinea corporis).These topical products are applied directly to the affected skin,allowing terbinafine to penetrate the site of infection and exert its antifungal effects.

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2.Custom Compounding:Terbinafine powder may be utilized by compounding pharmacies and healthcare providers to prepare customized formulations tailored to the specific needs of individual patients.These compounded products can include specialized creams,powders,or solutions for the treatment of fungal infections in areas that may require unique formulations,such as the scalp,nails,or mucous membranes.


3.Research and Development:The versatile nature of terbinafine powder makes it a valuable component in pharmaceutical research and development.Scientists and researchers may use terbinafine powder to formulate and test new drug delivery systems,enhance the stability and bioavailability of existing formulations,or explore novel therapeutic applications in the field of antifungal pharmacology.Veterinary Medicine:Terbinafine powder may also find application in veterinary medicine for the treatment of fungal infections in animals,including dermatophytosis and other fungal skin conditions.
4.Veterinary formulations,such as creams or powders,can be prepared using terbinafine powder to address fungal infections in companion animals and livestock

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In summary,terbinafine powder is a versatile and potent antifungal ingredient with diverse applications in pharmaceutical formulations,compounding,research,and veterinary medicine.Its broad spectrum of activity against fungal pathogens,coupled with its solubility and stability characteristics,makes it a valuable resource for addressing fungal infections in both human and animal health.

Specification

235(1)5xk

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