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Tropicamide Anticholinergic Agent for Eye Examination and Treatment Tropicamide Powder

Reference Price: USD 20-30/g

  • Product Name Tropicamide
  • CAS No. 1508-75-4
  • MF C17H20N2O2
  • MW 284.3529
  • EINECS 216-140-2
  • Solubility 0.2g/L(25 ºC)
  • Melting point 98 °C
  • Boiling point 492.8°Cat760mmHg

Detailed Description

Tropicamide, also known as Mydriacyl, is an anticholinergic medication used in ophthalmology to dilate the pupil and facilitate eye examinations. It is available as eye drops and produces rapid and temporary mydriasis (pupil dilation) and cycloplegia (paralysis of the ciliary muscle). These effects allow for better visualization of the lens, vitreous humor, and retina during various eye procedures and examinations.

Tropicamide is classified as an antimuscarinic drug, meaning it blocks the action of acetylcholine at muscarinic receptors. This mechanism of action results in the dilation of the pupil and temporary paralysis of the ciliary muscle when applied as eye drops. Due to its relatively short duration of effect, typically lasting between 4 to 8 hours, tropicamide is commonly used during eye examinations, such as dilated fundus examinations, to obtain a clear view of the structures at the back of the eye.

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Eye examinations that require mydriasis, such as fundus examinations and optometry assessments, benefit from the use of tropicamide. By dilating the pupil, tropicamide allows the ophthalmologist or optometrist to examine the retina, optic nerve, and other structures in the eye with greater ease and accuracy. Additionally, tropicamide can be used in the management of iris inflammation, providing relief and aiding in the healing process.

Tropicamide eye drops are typically applied directly to the eye, and their effects become noticeable within approximately 40 minutes. The duration of action can last up to a day, allowing for an extended examination period if necessary.

Aside from its diagnostic uses, tropicamide may also be employed before or after eye surgery. By inducing cycloplegia and mydriasis, tropicamide helps prepare the eye for surgical procedures and facilitates postoperative assessment.


Tropicamide is absolutely an valuable tool in ophthalmology for facilitating eye examinations. By inducing mydriasis and cycloplegia, tropicamide allows for better visualization of the eye's posterior structures during procedures such as dilated fundus examinations. Its rapid onset of action and relatively short duration make it a preferred choice for ophthalmologists and optometrists. Tropicamide's versatility extends beyond examination purposes, as it can also be utilized in the treatment of iris inflammation. When used appropriately, tropicamide plays a crucial role in ensuring accurate diagnoses and effective management of various eye conditions.
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